To access free multiple choice questions on this topic, click here. Erythema multiforme is a distinct dermatologic hypersensitivity pathology characterized by cutaneous or mucous lesions and eventually it can also involve both. This means that the body is sensitive to something that causes the skin and mucous membranes to react. It presents with a skin eruption characterised by a typical target lesion. It occurs predominantly in young adults, is slightly more common in females, and the incidence is somewhere between 0. Minor erythema multiforme case report medcrave online. Erythema multiforme is associated with an acute onset. These lesions are often accompanied by erosions or bullae involving the oral, genital, andor ocular mucosae picture 2ac. Oral erythema multiforme em is considered as a third category of em other than em minor and major. The term erythema multiforme em includes a wide and controversial variety of clinical expressions at the present time. What is erythema multiforme erythema multiforme is a hypersensitivity reaction usually triggered by infections, most commonly herpes simplex virus hsv. Pdf the term erythema multiforme em includes a wide and controversial variety of clinical expressions. It is an uncommon disorder, with peak incidence in the second and third decades of life. Some spots can have a small blister or scab in the middle.
Erythema multiforme minor erythema multiforme major stevensjohnson syndrometoxic epidermal polimoorfo panniculitis erythema nodosum acute generalized exanthematous pustulosis. Erythema multiforme minor presents as a bulging, rashlike lesion that is red, pink, purple, or brown. Pdf erythema multiforme is an acute or chronic inflammatory mucocutaneous manifestation of variable morphological expression. Retrieved 28 november erythema multiforme em erythema multiforme minor of the hands note the blanching centers of the lesion specialty dermatology erythema multiforme em is a skin condition of unknown cause. Eritema multiforme wikipedia, a enciclopedia livre. It is a hypersensitivity reaction associated with certain infections, vaccinations, and, less commonly, medications. Erythema multiforme for parents nemours kidshealth. Erythema multiforme symptoms, diagnosis and treatment.
Management of erythema multiforme associated with recurrent. It appears as a symmetrical rash and may include the mucous membrane lesions. Erythema multiforme is usually mild erythema multiforme minor with only skin involvement, and clearing up in days to weeks. Erythema multiforme airuhtheemuh multehformee starts with pink or red blotches. Pdf erythema multiforme is an eritfma or chronic inflammatory mucocutaneous manifestation of variable morphological expression. Access a collection of canadian resources on all aspects of english and french, including quizzes. Erythema multiforme em is an acute, selflimiting disease of the skin and mucous membranes described by hebra in 18661. Em is clinically characterized by a minor form and a major form.
Erythema multiforme em is an acute, immunemediated condition characterized by the appearance of distinctive targetlike lesions on the skin picture 1ah. This study revises the em minor characteristics according to the. Retrieved 28 november erythema multiforme minor erythema multiforme major stevensjohnson syndrometoxic epidermal necrolysis panniculitis erythema nodosum acute generalized exanthematous pustulosis. Erythema multiforme is an acute skin condition characterized by targetoid lesions. It essentially touches the skin with typical lesions symmetrical. Eritema multiforme minor pdf republic of fenerbahce. Although the existence of photodistributed erythema multiforme has been recognized for years, few cases have been described to date. Erythema multiforme is a skin condition considered to be a hypersensitivity reaction to infections or. Erythema multiforme minor pdf download lcanordaychin. Em with mucosal involvement is known as erythema multiforme major, and without mucosal disease it is referred to as erythema multiforme minor. Recently, erythema multiforme has been classified as minor, major, stevensjohnson syndrome or toxic epidermal necrolysis, where erythema multiforme minor is the mildest type of lesion and toxic epidermal necrolysis the most severe2,3 table 1. It is acute and selflimiting, usually resolving without complications erythema multiforme is divided into major and minor. Erythema multiforme em is an interesting dermatologic disease which has oral manifestations.
It presents a diagnostic dilemma because the oral cavity has the ability to produce varied manifestations. Iphoto fotobuch in pdf symptoms include fever, malaise, sore throat, cough, vomiting, diarrhea, arthralgia, and myalgia. Two types, one mild to moderate and one severe, are recognized erythema multiforme minor and erythema multiforme major. Las formas leves normalmente no requieren tratamiento. Erythema multiforme is usually a reaction of the skin and mucous membranes that occurs suddenly. Erythema multiforme em is typically an acute, selflimiting but often relapsing, mucocutaneous inflammatory condition. Erythema multiforme british association of dermatologists.
Abstract erythema multiforme em is an uncommon, immune. Erythema multiforme em is a skin condition of unknown cause. It is usually circular, less than 3 centimeters in size, and similar to a bullseye in appearance. Erythema multiforme em is a rare skin disorder that mainly affects children. Episodic angioedema with eosinophilia hereditary angioedema. Eritema multiforme manifestaciones oculares provisu. Em is said to be rare in childhood, and very few paediatric series concern em. A abordagem dos aspectos atuais do eritema multiforme e a. Diagnosis, classification, and management of erythema.
Erythema multiforme may be a mild condition erythema multiforme minor, or it may be a severe, possibly lifethreatening condition erythema multiforme major or stevensjohnson syndrome. Erythema multiforme em is an acute mucocutaneous disease that characterized by being selflimiting and immunemediated. It causes a rash of spots with dark centers and pale red rings that look like a target or bullseye. Erythema multiforme stevensjohnson syndrome, erythema multiforme major, erythema multiforme minor, herpesinduced em major, herpesassociated erythema multiforme, druginduced stevensjohnson syndrome 3. Erythema multiforme is a reactive mucocutaneous disorder in a disease spectrum that comprises a selflimited, mild, exanthematic, cutaneous variant with minimal oral involvement em minor to a. Toxic epidermal necrolysis, manifested by widespread epidermal desquamation, is the. This study revises the em minor characteristics according to the most important publications found in literature. Erythema multiforme is an acute inflammatory skin disease where 90% of the minor cases follow outbreaks of herpes simplex. Erythema multiforme em is an acute, selflimited, and sometimes recurring skin condition that is considered to be a type iv hypersensitivity reaction associated with certain infections, medications, and other various triggers. Revision y puesta al dia gavaldaesteve, carmen erythema multiforme. Patients present with oral and lip ulcerations typical of em but without any skin target lesions. When seen in adults, it usually occurs between the ages of 20 and 40, although it can happen to people of any age.
Clinical features, diagnosis, and treatment of erythema multiforme. Erythema multiforme major, minor, and persistent variations. Steven johnson syndrome sjs, toxic epidermal necrolysis ten and erythema multiforme for usmle duration. Erythema multiforme major is the term used to describe em with severe mucosal involvement and.